Gatsby Computational Neuroscience Unit
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Neural Activity and BOLD Functional MRI Workshop

27 February - 1 March 2006
By invitation only

Venue: B10 Seminar Room, Alexandra House, 17 Queen Square, London, WC1N 3AR

Please see map at: http://www.ucl.ac.uk/images/map_arounducl_l.jpg

Supported by the Gatsby Charitable Foundation


PROGRAMME

[45 minute talks plus 15 minutes for discussion]

Sunday 26 February

 

18.00 - 20.00

Welcome Drinks

 

4th Floor, Alexandra House, 17 Queen Square

 

 

Monday 27 February

 

10.00 - 10.30

Tea, coffee and Welcome (Peter Dayan and Bob Turner)

Session 1

Neuronal functional biochemistry

Chaired by Bob Turner

10.30 – 11.30

David Attwell – The cellular distribution of energy use in the CNS and the matching of blood supply to energy usage

11.30– 12.30

Karl Kasischke – NADH as a functional imaging signal

12.30 – 13.30

Lunch

13.30– 14.30

Richard Buxton – The thermodynamics of thinking: Is CBF regulation maintaining the ratio [O2]/[CO2] in cells?

Session 2:

Neural activity, oxygen delivery and cerebral blood flow

Chaired by Jason Berwick

14.30– 15.30

Martin Lauritzen – Possible neurophysiological mechanisms for positive and negative BOLD contrast signals explored in rat sensory and cerebellar cortex

15.30 - 16.00 Tea and Coffee

16.00 – 17.00

Roger Springett – Mitochondrial oxygenation in the brain

17.00 – 18.00

John Mayhew – OIS and MRI measurements: towards a biophysical model of the relationship between neural activity and the BOLD signal

 

 

Tuesday 28 February

 

Session 3:

What kind of neural activity does BOLD signal indicate?

Chaired by Martin Lauritzen

9.15-10.15

Fahmeed Hyder – Energetics of neural populations by fMRI: Towards quantitative neuroimaging

10.15-11.15

Ralf Galuske – Hemodynamic signals and local neuronal processing

11.15-11.45

Tea and Coffee

11.45-12.45

Amir Shmuel – Neuronal correlates of negative BOLD responses in monkey visual cortex

12.45 – 14.30

Lunch

14.30 – 15.30

Geraint Rees - How much information can be extracted from the BOLD signal?

Session 4:

Oxygen extraction

Chaired by Risto Kauppinen

15.30 – 16.30

Peter van Zijl – Coupling of flow and oxygen metabolism as studied by BOLD fMRI. What can we measure and what not?

16.30 – 17.00

Tea and Coffee

17.00- 18.00

Bruce Pike – Sensitivity of the BOLD fMRI activation response to global vasodilation

20.00 - finish

Dinner - Trattoria Verdi Restaurant, 110 Southampton Row, London, WC1 4BL

 

 

Wednesday 1 March

 

Session 5:

Spatial and temporal aspects of fMRI signal

Chaired by Roger Ordidge

9.30 – 10.30

Afonso Silva – Spatial and temporal characteristics of the functional hemodynamic response: insights from fMRI and two-photon microscopy

10.30- 11.30

Arno Villringer - Adding meaning to the fMRI signal

11.30 – 12.00

Tea and Coffee

12.00 – 13.00

Robert Turner – How the brain is fed and drained: cerebral vascular geometry and its implications for BOLD spatial and temporal resolution

13.00 – 14.00

Lunch

14.00 – 15.00

General discussion (available)

 

 

 

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