Spatial maps and path integration in the entorhinal cortex

May-Britt Moser

Centre for the Biology of Memory, NTNU, Trondheim , Norway

Converging evidence points to the recurrent networks of the hippocampus as a possible attractor-based neural network capable of performing both pattern completion and pattern separation. In my talk, I will show how the recurrent network of the CA3 subfield of the hippocampus may store both continuous and discontinuous representations of the animal’s environment, and how transitions between these representations in the hippocampus may reflect alignment of a universal path-integration based spatial map upstream in the medial entorhinal cortex. In the final part of the talk, I will present evidence for a role of both dentate gyrus and CA3 in orthogonalization of inputs to the hippocampus.