Neural circuits display complex spatiotemporal patterns of activity on
the millisecond timescale during behavior. Understanding how these
activity patterns drive behavior is a fundamental problem in
neuroscience, and remains a major challenge due to the complexity of
their spatiotemporal dynamics. I will describe a strategy for
"all-optical" simultaneous imaging and manipulation of patterns of
activity in neural circuits in vivo with single-spike and
single-neuron precision. This approach should open up new experiments
for probing the nature of the neural code during behaviour.
 Packer et al. Nature Methods 12: 140-6 (2015).