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Gatsby Computational Neuroscience Unit
Alexandra House, 17 Queen Square, LONDON, WC1N 3AR, UK
Tel: +44 (0) 20 7679 1176, Fax +44 (0) 20 7679 1173, admin@gatsby.ucl.ac.uk, www.gatsby.ucl.ac.uk

 

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WORKSHOP ON:
CENTRAL PROBLEMS IN SINGLE CELL COMPUTATION


16-18 September 2002
By invitation only

Venue
B10 Seminar Room, Alexandra House, 17 Queen Square, London, WC1N 3AR


Predicting the function of neurons from their morphology
Michael Häusser, Department of Physiology, UCL, UK
Co-author: Arnd Roth
, Max Planck Institute for Medical Research, Heidelberg, Germany
How does dendritic morphology shape the functional architecture of different types of neurons? Using compartmental models of reconstructed neurons endowed with the same distribution of active conductances we isolate morphology as the only variable. We show that the spread of subthreshold synaptic potentials, the forward- and backpropagation of action potentials in dendrites as well as the interaction of somatic and dendritic action potential initiation sites is tuned by subtle details of the dendritic branching pattern.