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WORKSHOP ON:
CENTRAL PROBLEMS IN SINGLE CELL COMPUTATION
16-18 September 2002
By invitation only
Venue
B10 Seminar Room, Alexandra House, 17 Queen Square, London, WC1N 3AR
Predicting the function of neurons
from their morphology |
Michael Häusser, Department
of Physiology, UCL, UK
Co-author: Arnd Roth, Max
Planck Institute for Medical Research, Heidelberg, Germany |
How does dendritic morphology shape the
functional architecture of different types of neurons? Using compartmental models of
reconstructed neurons endowed with the same distribution of active conductances we isolate
morphology as the only variable. We show that the spread of subthreshold synaptic
potentials, the forward- and backpropagation of action potentials in dendrites as well as
the interaction of somatic and dendritic action potential initiation sites is tuned by
subtle details of the dendritic branching pattern. |
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