Gatsby Computational Neuroscience Unit
Alexandra House, 17 Queen Square, LONDON, WC1N 3AR, UK, Tel: +44 (0) 20 7679 1176, Fax +44 (0) 20 7679 1173,



B10 Seminar Room, Alexandra House, 17 Queen Square
London, WC1N 3AR

Supported by The Gatsby Foundation

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Acetylcholine and Norepinephrine in Covert Attention and Attention Deficits

Richard Marrocco
Department of Psychology, Institute of Neurosience, University of Oregon, USA

Work in my lab work uses a comparative approach to understand the neural mechanisms that underlie reflexive and voluntary attention.  To this end, we use pharmacological, physiological and behavioral manipulations to reveal the components of attention, their neurotransmitter dependences, and the structures that direct their allocation to objects in visual space.  I will present data that summarize our recent findings on voluntary attention and the neuropharmacology of the parietal cortex.  These and previous findings have led us to predict that human reflexive attention deficits should be mediated by abnormal noradrenergic function, and I will report recent data for human ADHDs that strongly support this expectation.